Toward a functional characterization of blood monocytes.
نویسندگان
چکیده
Pirrotta L et al. Patients with allergic contact dermatitis to nickel and nonallergic individuals display different nickel-specific T cell responses. Evidence for the presence of effector CD8+ and regulatory CD4+ T cells. J Invest Dermatol 1998; 111: 621–628. 2 Artik S, von Vultée C, Gleichmann E, Schwarz T, Griem P. Nickel allergy in mice: enhanced sensitization capacity of nickel at higher oxidation states. J Immunol 1999; 163: 1143–1152. 3 Schmidt M, Raghavan B, Müller V, Vogl T, Fejer G, Tchaptchet S et al. Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel. Nat Immunol 2010; 11: 814–819. 4 Wells GC. Effects of nickel on the skin. Br J Dermatol 1956; 68: 237–242. 5 Picardo M, Zompetta C, De Luca C, Cristaudo A, Cannistraci C, Faggioni A et al. Nickel–keratinocyte interaction: a possible role in sensitization. Br J Dermatol 1990; 122: 729–735. 6 Goebeler M, Roth J, Bröcker EB, Sorg C, Schulze-Osthoff K. Activation of nuclear factor-kappa B and gene expression in human endothelial cells by the common haptens nickel and cobalt. J Immunol 1995; 155: 2459–2467. 7 van der Aar AM, Sylva-Steenland RM, Bos JD, Kapsenberg ML, de Jong EC, Teunissen MB. Loss of TLR2, TLR4, and TLR5 on Langerhans cells abolishes bacterial recognition. J Immunol 2007; 178: 1986–1990.
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عنوان ژورنال:
- Immunology and cell biology
دوره 89 1 شماره
صفحات -
تاریخ انتشار 2011